A new paper in the ERC BOOST and FARE GRACE projects framework has just been published!

We are proud to share our last publication entitled “PEG-Coated Large Mesoporous Silicas as Smart Platform for Protein Delivery and Their Use in a Collagen-Based Formulation for 3D Printing”. The article has been published in the Special Issue of “Ordered Mesoporous Materials” of the International Journal of Molecular Sciences. 

It reports the design and the development of mesoporous silica with pores up to 23 nm coated with a pH-sensitive polymer, PEG, able to host large molecular weight molecules such as growth factors in their pores and release them in response to a pH decrease, in an attempt to mimic the growth factors release in bone tissue under the acidic pH generated by the resorption activity of osteoclasts. Furthermore, PEGylated silicas have been incorporated in a hybrid Type I collagen suspension to fabricate 3D printed composite scaffolds for tissue regeneration.

Access to the full article here: https://www.mdpi.com/1422-0067/22/4/1718